Thiazolidinediones: metabolic actions in vitro
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چکیده
منابع مشابه
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Thiazodinedione (TZD) agonists of the peroxisome proliferator activated receptor gamma (PPAR ) exert metabolic effects in glial cells. In primary astrocytes, TZDs are cytoprotective and have anti-inflammatory actions; in contrast, in glioma cells TZDs are cytotoxic. Although PPAR is considered their primary target, TZDs including pioglitazone and troglitazone also bind to a mitochondrial protei...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2002
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-002-0899-1